1o root causes of fibromyalgia


Just a quick article from one of my fav functional medicine practitioner’s (Amy Myer’s) on possible root causes of fibromyalgia. None of these surprise me after my 20 years of research on this subject, or my holistic nutrition schooling thus far. I myself have gluten intolerance, MAJOR candida overgrowth (hard to get rid of, can take 2 years of a strict strict diet), an underactive thyroid, magnesium, vitamin D and B12 deficiency which I take supplements for, leaky gut (which normally happens because of candida), adrenal fatigue (more like exhaustion – I’m on 2 herbal remedies for this), and I still need to get my toxin levels checked! As you can see, there is no one cause, and it can take a LONG time to start feeling better as you try different ways of treating each issue. Not a fun time! I ate a pita sandwich tonight and shouldn’t have, and now I’m suffering big time with a HUGE stomach ache and major heartburn because of the gluten in the bread, which then aggravates the candida AND the leaky gut! Yikes! On a plus side, I saw my pain specialist today for my injections and they helped a bit, but she thinks the severe neck pain is from taking notes in class, sitting at the computer doing homework, and studying, so back to similar issues I had while working full time. GREAT! How do I solve those issues?! Every day is a learning process with this illness, I tell ya!


Gluten Intolerance:

Gluten has been liked to more than 55 diseases and is often called the ‘big masquerader’. The reason for this is that the majority symptoms of gluten intolerance are not digestive in nature but rather neurological such as pain, cognitive impairment, sleep disturbances, behavioral issues, fatigue and depression.

Candida Overgrowth:

Candida is a fungus or yeast, and a very small amount of it lives in your intestines. However, when overproduced, candida breaks down the wall of the intestines and penetrates the bloodstream, releasing toxic byproducts into your body causing a host of unpleasant symptoms such as brain fog, fatigue, digestive issues, and pain. Virtually every one of my patients with fibromyalgia have had Candida overgrowth.


More than half of the people with thyroid issues have no idea they have one and 90% of these have hypothyroidism, or an underactive thyroid gland.  It is vital that your doctor check six different blood markers to measure your thyroid gland’s function. It’s imperative that your doctor use the optimal levels rather than the standard reference range when assessing and diagnosing thyroid disorders. Getting my patient’s thyroid levels into an optimal range, typically alleviates their fatigue, brain fog, sleep disturbances and depression.

Vitamin Deficiencies:

Magnesium, vitamin D and B12 deficiency are the most common vitamin deficiencies I see in those who have been diagnosed with fibromyalgia.  I have had several patients completely reverse their fibromyalgia symptoms with magnesium alone.  The best way to measure magnesium is a red blood cell (RBC) magnesium level, which can be tested through any conventional lab.

Small Intestine Bacterial Overgrowth (SIBO) and Leaky Gut:

There are more bacteria in us and on us then there are of our own cells.  When these bacteria get out of balance through use of antibiotics or a sugar-rich diet we can lose our ability to digest and absorb nutrients, particularly B12.  Gluten can cause SIBO and leaky gut and SIBO and leaky gut can lead gluten and other food intolerances.  It’s a catch-22 and a vicious cycle. You must ‘fix the gut’ first in anyone with fibromyalgia or any chronic illness.

Adrenal Fatigue:

Adrenal fatigue is a result of the chronic stress whether real or perceived. Chronic pain is a stress to the adrenal glands, though typically not the initial adrenal stressor.  The initial stressor is usually something such as food intolerances, Candida, mercury toxicity, vitamin deficiencies, or mycotoxins.  My goal is to support the adrenals with adaptogenic herbs while we search for the root cause of the stress and correct it.


Mycotoxins are very toxic substances produced by toxic molds.  Only about 25% of the population carries the genes to be susceptible to the effects of mycotoxins.  Conventional environmental mold testing only tests for levels of mold spores and does not test for mycotoxins.  I use a urine mycotoxin test in my clinic to determine if someone has been exposed to toxic molds.

Mercury Toxicity:

I recommend that all my patients find a biological dentist and have their mercury amalgam fillings removed.  Mercury is toxic to our bodies and can be one piece of the puzzle for those with fibromyalgia and other chronic illnesses such as chronic fatigue syndrome, autoimmune diseases, neurological disorders and cancer. I then recommend heavy metal testing using a pre and post DMPS urine challenge test.

MTHFR Mutations:

This is a genetic test you can get though any conventional lab.  The more mutations you have at the MTHFR gene the less able you are to methylate and detoxify particularly toxins such as mercury and lead. The more mutations you have at this gene the higher your requirements for methyl-B6, methyl-B12 and folinic acid in order to keep your detoxification pathways working properly.

Glutathione Deficiency:

Glutathione, a molecule, is the most critical part of our body’s detoxification system.  Glutathione gets recycled in our body unless our toxic burden gets to high or we lack GSTM1 and GSTP1, the enzymes needed to recycle and produce glutathione. Taking glutathione or the precursors (NAC, alpha lipoic acid, milk thistle) often help my patients dramatically with fatigue.

As you can see from the above list, many of these causes are interrelated and often there is no one single root cause to fibromyalgia or any chronic illness.  It is a combination of several or possibly all of the above.  Because getting to the root cause can be complex, after what I have studied at school, I recommend that you find a functional medicine physician or a naturopath in your area to help uncover the root cause for you.  You do not need to suffer needlessly or mask your symptoms with pain medication and antidepressants.  There are doctors out there who can help you!

xoxo Lex


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